• Yellow fever is an acute viral hemorrhagic disease transmitted by infected mosquitoes. The "yellow" in the name refers to the jaundice that affects some patients.
  • The virus is endemic in tropical areas of Africa and Latin America, with a combined "at risk"-population of over 900 million people.
  • WHO estimates that 200,000 cases of yellow fever, causing 30,000 deaths, occur each year.
  • There is no specific treatment and vaccination is the single most important preventive measure.
  • The vaccine is safe, affordable, and appears to provide protection for > 30–35 years.
  • The number of yellow fever cases has increased over the past two decades due to declining population immunity to infection, deforestation, urbanization, population movements and climate change.